Breaking News from ADA 2021


 

This page was last updated at 7:35 am PT June 29, 2021.

Editor’s Note: This article was updated regularly with breaking news and announcements during the course of the ADA Scientific Sessions Conference. Coverage of the ADA Scientific Sessions is brought to you by the ADA x BT1 Collab.


 

Tuesday, June 29, 2021

  • Walmart announced the launch of the first-ever private brand analog insulin.  The new private label ReliOn NovoLog Insulin (insulin aspart) injection, manufactured by Novo Nordisk, is available in Walmart pharmacies this week, and Sam’s Club pharmacies in mid-July across the United States. The new offering includes insulin vials at $72.88 and FlexPen packages at $85.88, saving customers between 58% to 75% off the cash price of branded analog insulin products.
  • Data from the wide-scale, global SURPASS Clinical trial for the novel dual GIP/GLP-1, Tirzepatide, showed significant reductions in A1C and body weight for people with Type 2 diabetes when compared to several different treatments including GLP-1, basal insulin, and metformin. While the news reported on Saturday centered on the first phase, SURPASS-1, today’s news encompasses all current 5 phases of the trial. Notable changes in A1c for some of the trials were: SURPASS-1: When compared to placebo, 92% of patients achieved an A1C <7% and 52% achieved an A1C <5.7, the level for people without diabetes.
    • SURPASS-2: When compared to semaglutide, 92% of patients achieved an A1C <7%, and 51% achieved an A1C <5.7, the level for people without diabetes.
    • SURPASS-3: When compared to insulin degludec, 93% of patients achieved an A1C <7%, and 48% achieved an A1C <5.7, the level for people without diabetes.
    • SURPASS-5: When compared to insulin glargine, 97% of patients achieved an A1C <7%, and 62% achieved an A1C <5.7, the level for people without diabetes.

Monday, June 28, 2021

  • Medtronic announced key clinical data from #ADA2021. Presentations illustrated increases in Time in Range when using an InPen smart insulin pen, safety of an extended-wear infusion set that lasts up to 7 days, and patient satisfaction with the longer-wear infusion set.
  • Data from a large-scale international AMPLITUDE O trial showed that use of the once-weekly injectable efpeglenatide, a GLP-1,  significantly reduces the first occurrence of adverse cardiovascular events such as heart attack, stroke, or death and a decrease in the progression of kidney disease in patients with Type 2 diabetes. The 2-year trial was conducted in 8 countries and had over 4,000 participants. Compared to those who took the placebo, patients who took the GLP-1 had a 27 percent lower risk of a heart attack, stroke, or cardiovascular death. In regards to kidney disease, they displayed a 32 percent lower risk of developing it. There were no serious side effects reported.
  • New research from the Centers for Disease Control and Prevention (CDC) revealed income-related inequalities in diabetes have widened over the past decade, from 2001 to 2018. Through that time period, diabetes was more prevalent in low-income communities, but income inequalities narrowed between 2001-2011 and then widened in 2011-2018. Compared to people in high-income households, the prevalence of diabetes increased by 40 percent, 74.1 percent, and 100.4 percent for those from middle-income, near-poor, and poor, respectively.

Sunday, June 27, 2021

  • Results from DARE-19, the first large randomized clinical trial to assess (SGLT2) inhibitors in patients with and without type 2 diabetes hospitalized with COVID-19 showed that Dapagliflozin is well tolerated.
  • In an early morning session at ADA titled “Who Should Loop?”, providers and patients gave perspectives on the current state of DIY Looping systems in 2021 and discussed the pros and cons of the various systems.
  • A discussion about the progression of Type 2 diabetes in children/youth (aged 10-19) showed that compared to adults: diabetes in children is more aggressive, beta-cell function decreases faster even with medications, and complications such as retinopathy and cardiovascular issues are accelerated and usually found at diagnosis. The discussion also discussed new and ongoing trials to increase the chances of approval of the use of Type 2 diabetes, typically used for adults, for children.

Saturday, June 26, 2021

Friday, June 25, 2021

Thursday, June 24, 2021

 


For Full ADA 2021 Coverage from Beyond Type 1 CLICK HERE

WRITTEN BY Beyond Type 1 Editorial Team, POSTED 06/25/21, UPDATED 07/22/21

This piece was authored collaboratively by the Beyond Type 1 Editorial Team. This includes Eugenia Araiza, Todd Boudreaux, Mariana Gómez, Kayla Hui, T'ara Smith and Ginger Vieira.